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DNA ligases seal five′-PO4 and 3′-OH polynucleotide ends via 3 nucleotidyl transfer ways involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are essential guardians of genomic integrity, and ligase dysfunction underlies human genetic illness syndromes. Crystal buildings of DNA ligases bound to nucleotide and nucleic acid substrates have illuminated how https://elliotwtplf.blazingblog.com/28069390/the-smart-trick-of-secure-betting-platform-that-no-one-is-discussing

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